During the last two decades manufacturing technologies have been through a number of revolutions. The most visible is Additive Manufacturing, called 3D printing when addressing to the general public; it is not the only one. This rapid change in manufacturing technologies is deeply modifying the interactions all across the chain of individuals and companies involved in the development of space hardware. This new situation requires also a rapid adaptation of those same individuals and companies to maximise the benefits brought by such revolution. The well-established rules for materials and processes selection, materials evaluation, processes validation, design rules, parts verification and qualification in space industry need to be all revisited and challenged. The presentation will highlight the main trends followed within ESA, the European Space Agency to proactively adapt to the new situation.